THE COLOMBO PAPERS

DEREK DILLON'S UNPUBLISHED ARTICLES


Quantum Biophysics of
the Homeopathic Ozone Effect©

the quantum wave properties of DNA
During the flurry of papers which appeared in the 1970s on coherent behavior in biological systems (e.g., Fröhlich, 1968, 1969, 1970, 1975, 1983), the International Journal of Quantum Chemistry published a mathematical model of how the genetic molecule, DNA, receives information from the ambient electromagnetic field, incorporates that information into its internal dynamics during replication, and radiates coherent waves in response (Paine and Pensinger, 1979). This model of DNA’s quantum wave processes relies upon the derivation of an equation descriptive of a harmonic oscillator. Such oscillators vibrate with properties associated with the production of musical sound. The fundamental oscillator is a parcel of pi-electrons in the free-electron gas enveloping the molecule. This parcel is characterized as undergoing temperature oscillations in response to fluctuations in the ambient electromagnetic field. An ensemble effect is generated in the collection of parcels forming the electron cloud which carries the molecule to its critical temperature, whereupon helix-coil transition begins and replication is initiated. As replication of the nucleotide sequences transpires, temperature oscillations in the free-electron gas environment of the molecule’s pi-stacks generate pressure waves in coherent trains which radiate out from the molecule affecting phase boundaries such as the cell membrane. (Lipton, 1986, presents a notion of frequency response selectivity by the cellular membrane similar to fractal entrapment. Pensinger, Oliphant, and Paine, 1981, suggest that the coherent waves generated by DNA exercise a direct “bias” control over the cell membrane potential, and hence play an indirect timing role in ionic diffusion processes by rate limiting the flow of free electrons in the membranes’s active transport system. It is possible that the coherent waves stabilize -- as in Bosè-Einstein condensation by providing energy exceeding a critical value -- some vibratory mode of dipole oscillation of electric waves in the cell, which, in turn, control variations of membrane potential.) These radiating coherent waves have four degrees of freedom, each correlated with one of the four nucleotide pairs. Hence, since coherency is one of the defining characteristics of acoustic waves, and since these waves are generated by an ensemble of harmonic oscillators, it can be said, according to the dictates of this model, that the coherent waves carry an analogue of the music of the nucleotide pairs (a pulsed audiogram) into the cellular environment. One may hypothesize that the stereochemical information transfer accomplished by DNA replication is primarily associated with fulfilling the requirements of functional specificity, while the genetic information transfer accomplished by the propagating coherent waves is primarily associated with fulfilling the requirements of functional integration. (For similar perspectives, see McClare, 1974; Robinson, 1985; and Tian, 1989.)

According to Paine and Pensinger, the double-helix of the molecule coils itself around a superconductant core of pi-stacks (free electrons from the pi-orbitals of atoms composing the ladder of nucleotide pairs). This property of superconductivity dictates that the frequency window of response to variations in the ambient electromagnetic field be very narrow. Moreover, the status of superconductivity allows for the building up of a very weak signal. When the mass properties of DNA molecules of different histological type -- e.g., collagen cell DNA, muscle cell DNA -- are considered, it becomes apparent that each type of tissue DNA must have a unique natural frequency, wavelength, waveform, and intensity determining its window of response, that is, the characteristic signature of radiational properties absorbed and emitted by the molecule. The response window is, therefore, a unique signature of identity. Since histocompatibility is dependent upon a defining identity tag, it is possible to consider the DNA molecule’s response window as the fundamental signifier for immunological isolation.

The rate of temperature oscillation of the free-electron parcels in the molecule’s pi-stack electron cloud is a variable quantity -- varying, that is, in response to fluctuations in the ambient electromagnetic field. In the ensemble of parcels, this variable rate sets the time rate of change of helix-coil twisting. It is, therefore, a clock governing the replication of genetic information -- the rate of which can be altered by environmental factors. This clock, which is the rate of free-electron parcel oscillation, may be regarded as the fundamental intracellular Zeitgeber or time-giver.

In the quantum processes governing the DNA molecule’s response to changes in its electromagnetic environment, therefore, we have two correlated properties: a clock and a signature for self-identification. Anything that shifts either of these two properties outside their natural boundaries of operation may be considered pathogenic. Indeed, the recording of chronic stress on the quantum level of the organism would most fundamentally involve driving the free-electron parcels’s oscillation farther and farther away from its natural rate, first changing the velocity of DNA replication, later disrupting the timing of cellular metabolic processes, and ultimately leading to morphological alterations. A shift in the DNA molecule’s frequency response window -- thus altering the fundamental signifier for self-identification -- would make the molecule immunologically alien, thereby alerting the body’s immune system, leading to the formation of autoantibodies, and culminating in the formation of anti-DNA-antibodies.

The onset of degenerative disease, then, can be regarded as beginning with a disruption of the quantum level frequency parameters governing isolation and timing of biological processes. As each tissue type exhibits a unique frequency regime, the different sets of symptom complexes, characteristic of given degenerative diseases, would have their origins in different patterns of disruption of the various frequency regimes exhibited by the array of tissue types constituting the organism. Though each degenerative disease has its unique march of pathogenic onset and its unique symptomatology, nonetheless, all would have a common origin in disruption of the quantum frequency parameters governing biological isolation and timing.

Homeopathic cure, therefore, would involve returning those frequency parameters to their natural values. As the march of symptom-complex onset in any given degenerative disease would have its origins in a unique pattern of frequency regime disruption -- i.e., duration, periodicity, intensity, spread across the array of affected tissue types -- the patterned unfolding of the symptomatology of the disease would constitute a gestalt uniquely correlated with frequency shifts responsible for onset of the disease.

symptoms and the homeopathic medical model
The basic mental transposition required to understand Hahnemann’s Law of Similars involves reconceptualizing the relation of pathology to symptoms. Allopathic medicine views symptoms as caused by pathology, as an expression of pathology. But is this really the case? Pick up Current Diagnosis and Treatment and study, in the account of any disease, the “pathology” section in relation to the “signs and symptoms” section. Is there a direct one-to-one cause-and-effect relation? No. Most of the signs and symptoms are caused by immune system responses. Just as the homeopath says: symptoms are the body’s attempt to cure itself. If pathology results from frequency shifts away from the normative, and symptoms are an expression of pathology, then how could like cure like? Like would only drive the frequency farther away from the normative. But if symptoms are an expression of the body’s defense mechanisms, then substances that produce the same symptoms in a healthy person would act against the frequency shift, carrying it back to the normative value. Symptomatology is not an expression of pathology, but a reaction against pathology. Allopathic medicine makes a clear and explicit distinction between “signs” and “symptoms”, which in some classes of instances may not be fully justifiable. Allopathic medicine makes no similar clear and explicit category distinction between symptoms arising from trauma and symptoms arising from disease: both types of symptoms are symptoms. This lack of categorical bifurcation may also not be fully justifiable.

a multivalued quantum reference space in biological systems
Information exchanged through stereochemical metabolic, hormonal, hematopoietic, lymphatic, muscular, neuronal, and immunological mechanisms is single-valued. Frequency correlates of this single-valued stereochemical information are “stacked” as a multivalued composite (via the biophysics superposition of “spontaneous fusion”) in the referencing quantum domain. The multivalued -- different rules of logic from the binary, the Boolean, the digital, i.e., m-valued truth systems first described in the 1920s (Post, 1921) -- reference space keeps a running composite accounting of all information exchanges on superordinate scale levels. Specificity of function requires single-valued information; functional integration requires multivalued information. Quantum mechanical localization and fusion -- decomposition and recomposition of the supersymmetry space, not a collapse of a probability wave function -- transpose the information between these two modalities, which Robert O. Becker called “digital and analog” (Becker, 1974) and Albert Szent-Györgyi called “alpha and beta states” (Szent-Györgyi, 1976). A detailed account of this general notion is provided in the discursive sections of The Moon of Hoa Binh (Nha Trang and Pensinger, 1994).

physical substrate of the multivalued reference space
Superconductant DNA’s pi-electron parcel temperature oscillations -- as intracellular Zeitgeber -- govern DNA-generated coherent waves which structure water inside the protein cylinder of cellular microtubules. These microtubules act as wave guides by selecting for wave trace velocities. This quasi-superradiance -- thermal energy transformed to coherent “light” pulses, the transformation involving intermolecular electron transport (Foster, 1969 and Slifkin, 1971) and a process at the submolecular level analogous to the functioning of a screen grid in a radio beam power tube -- mediates a self-induced transparency (microtubules conduct coherent pulses like fibre-optic cable) necessary for the aggregate cytoskeleton to function as an “optical” computer (Hammeroff, 1987 and Hammeroff, Rasmussen, and Mansson, 1988 and Penrose, 1994). The cellular automata engaged in mutual “switching” to induce self-organized activity patterns perform pure multivalued wave-effect processing: no binary switches are involved. These factors underlie collective behaviors of neuronal, perineuronal, and somatic cell aggregates -- as well as the deterministic genetic adaptation of bacterial cell colonies (Lipkin, 1995). Why is this quantum level explanation required? Because thermodynamically-driven stereochemical lock-and-key-device processes do not, and, in principle, cannot, explain functional integration. What evidence do we have of this? The whole realm of degenerative disease is not understood, which means that growth-and-repair processes in organic systems are not adequately understood. Moreover, genetic variability of disease vectors is not merely a matter of misuse of antibiotics and random mutations; highly self-organized quantum exchange processes are at the root of it, implicating electromagnetic pollution, an ozone depletion-driven changing UV environment, and response of flora and fauna to the radiational impacts of recombinant DNA technologies.

homeopathic mechanism of action
The homeopathic substance acts on the multivalued reference space, not the single-valued frequency correlates of stereochemical information. The reference space -- sometimes referred to as “Chi” (Hammeroff, 1974) and often misconstrued as energy -- has properties similar to a holographic plate with a superposition of standing wave patterns registered upon it. This is recorded in the structured water aspect of cellular cytoplasm-cytoskeleton. The superconductant DNA-generated coherent waves project through, and structure, the cytoplasmic-cytoskeletal hologram in conveying integrative information (i.e., the genetic codes contained in the nucleotide pairs and transmitted as a wave transpose, as the frequency signifier for immunological self-identity, as the clock signals generated by the ensemble of pi-electron parcels in the DNA free-electron gas environment) to the cell membrane -- thus rate-limiting, via a bias control and Bosè-Einstein condensation, the “active transport system” governing osmotic nutrient transfer across the membranic phase boundary. Shifted DNA frequency parameters must become chronic to cause modification of the multivalued reference space. The dilute succussed homeopathic substance “imprints” its solvent (Becker, 1990) via the structured-water hydration shells of its molecules’ active atomic groups. Dilution plus succussion, by imprinting the solvent, converts the frequency information of the active substance into a form (2-valued into m-valued) that is readable by the multivalued reference space. Both “imprinting the solvent” and the “cytoplasmic-cytoskeletal hologram” partake of the reduced Brownian motion which structured water is an expression of. Hand-held succussion is known to be much more effective than machine succussion. Succussion progressively structures the water of the solvent via oscillatory processes of attraction and repulsion at very short distances (Israelachvili and McGuiggan, 1988 and Becker, 1990; for discussion of the role of structured water relative to inter-molecular charge transfer processes see Szent-Györgyi, 1960) in the bioelectromagnetic environment established by the hand-holder. Repeated dilution potentizes by imprinting the evermore structured (with repeated succussion) hydration shells of the active atomic groups. Imprinting is patterned reduction of Brownian motion. The less there is to pattern, the more easily is the pattern imposed, i.e., imprinted. Hence, the necessity of dilution for potentizing. Experimental studies of this can be done by machine potentizing various substances with varied environmental electromagnetic field parameters. What is being patterned is the free-electron clouds of the hydration shells. The pattern imposed is as much a temporal ordering, as a spatial one, i.e., not only constraining Brownian motion into minimized and regular spatial movement patterns, but also imposing regular time patterns on fluctuations.

symptom-complexes
The symptom-complex tied to a given homeopathic substance gives expression to a loss of frequency information on the multivalued reference space -- which information the active homeopathic substance returns to the reference space. Homeopathic symptom-complexes are asymptomatic as far as allopathic medicine is concerned. Allopathic symptoms occur with tissue pathology. The homeopathic symptom-complex occurs before tissue pathology exists -- as a result of frequency shifts becoming more and more chronic.

autogenic discharges
Autogenic Therapy’s (Luthe and Schultz, 1969-73 and Pensinger and Paine, 1977-78) medical model is required to fully understand the onset of homeopathic symptom-complexes. Chronic frequency-regime shifts manifest as homeopathic symptom-complexes in large measure as a result of patterned suppression of sub-clinical autogenic discharges characteristic of a given TYPE (physical type, temperamental type, psychological type, homeopathic substance type: “guna” in the Sanskrit). TYPE has to do not only with stereochemical genetic inheritance, but also with inherited wave properties of the quantum structure of the genome, miasmatic (i.e., inherited DNA frequency anomalies) components, and persistent quantum states of neuronal cell aggregates manifest via long-range phase correlation and cellular automata self-organization. The quantum mechanics of spontaneous neuronal discharge (and its interaction with the multivalued reference space) mediates the two-way psycho-somatic transposition. That is why homeopathic materia medica reads like accounts of psychological-temperamental types, rather than allopathic signs and symptoms.

homeopathic effect in ozone therapy and the multivalued reference space
The wide-ranging biological effects of therapeutic ozone, particularly those associated with a homeopathic-like healing crisis, are on the same order of magnitude as those associated with autogenic brain discharges, suggesting that ozone’s mechanisms of action must include direct engagement with those factors responsible for functional integration (Pensinger and Paine, 1980 and Pensinger, Oliphant, and Paine, 1981). Electron acceptors (like ozone) and electron donors (like glutathione, vitamins A, C, and E), be they oxidizing or anti-oxidizing, participate in intermolecular electron transport, if the subsystem-system-supersystem composite is so organized as to be in Szent-Györgyi’s “beta state” (Szent-Györgyi, 1957, 1968, 1972). Intermolecular electron transport is instrumental in establishing the physical substrate of the multivalued reference space via quasi-superradiance: much of Szent-Györgyi’s laboratory experimentation in relation to intermolecular electron transport involved study of processes underlying bioluminescence (Szent-Györgyi, 1960). One mechanism of action of the triatomic molecule, ozone, may be via enhancement of a compromised quasi-superradiance, and thereby a restoration of the information carrying capacity of the multivalued reference space. Three levels of temporal ordering characterize processes associated with the reference space; a carrier function, a function mapping intrasystemic information exchange, a function mapping intersystemic flows (Paine and Pensinger, 1979). Processes in the Earth’s atmosphere involving ozone metabolism can be described in these same general terms (Paine and Pensinger, 1977). This correspondence suggests the notion that processes occurring in the biological organism involving the multivalued reference space have analogues in equivalent processes performing similar functions in the Earth’s atmosphere -- and that the underlying logic of this equivalency is central to explaining the full range of ozone’s therapeutic effects on the biological organism. General principles of self-organization apply to multi-scale processes wherever they might be found.

ozone a Fourier-transform operator
What is not explained is how ozone oxidizes pathogens and antibodies non-specifically, but does not disrupt those structures required for normal function. This is a recognition issue: the essence of immune system function, most basically rooted in the quantum frequency properties of the multivalued reference space. The atmospheric analogue of these processes involves wave-trace-velocity recognition in (coherent) accoustically-modified gravity wave organization of ozone metabolism and transport across the tropopause boundary. Molecular biology would say equivalent wide-ranging recognition is impossible in organic systems because the multitude of lock-and-key recognition devices required would be too enormously complex. Lock-and-key recognition is specific recognition, not only in fit, but in location: binding sites. How do you get classes of non-specificity out of this specificity? But m-valued wave-functions simplify the identity tag business very greatly. Systemic integration has to do with the general properties of systems, which are non-specific and can be represented by invariants of permissible transformations (transformation is the geometrical way of saying algebraic function). The nest of non-specific invariants prerequisite to systemic integration in a given class of organic systems can be physically embodied as a class of superposed frequencies. By decomposition, the frequency-tagged structures participating in the given class can be identified. Therefore, again by decomposition, those frequency-tagged structures not participating in the given class can also be identified. Ozone may be a Fourier-transform operator on a frequency space, an operator with a composite wave-function embodying invariants prerequisite to systemic integration in a wide class of organic (and inorganic) systems. Were this the case, then ozone would target for oxidation any frequency-tagged structure which is not a decomposition element of its own wave-function. How would this frequency recognition relate to the process of oxidation? The stereochemical “fit” of a given lock-and-key device (largely a matter of the geometry of bond angles) is only the first “step” in a chemical transformation involving the interacting atomic groups. This transformation is geometrical in nature, as much as electromagnetic. But function is an algebraic way of saying geometrical transformation! So the total given transformation (not just the lock-and-key device) may have a wave-functional analogue physically embodied as a frequency tag. And likewise for the total transformational prerequisites of systemic integration in a given class of systems. The invariants of the frequency space itself define the regime by which specific stereochemical processes are integrated spatially and temporally! Clearly, ozone directly interacts with this frequency aspect of the organism and thereby distinguishes between cytoskeleton-possessing eukaryotic cells and non-cytoskeleton-possessing prokaryotic cells to oxidize only prokaryotes (bacteria, blue-green algae and viruses).


REFERENCES

Return to:
•Top
•The Colombo Papers -- Abstracts
•Home page
1